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The GBD estimated that TBI resulted in 5.490 million years lived with disability across surveyed countries in 2021 alone [3]

Meyer LM, Lfgren S, Ho YS, Lou M, Wegener A, Holz F, et al

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50 Subsequent studies have reported that metformin-treated patients experienced statistically significant reduced vitamin B 12 concentrations compared to those not prescribed the drug, 62 in geriatric patients 65 and in individuals with or without microalbuminuria