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One primary pathway involves endocrine disruption, where phthalates interfere with hormonal balance, particularly by reducing testosterone levels

However, it did not affect other cancer cell lines such as mouse mammary tumor (DA3), bronchioalveolar carcinoma (H322), human hepatocellular carcinoma (HepG2), human breast carcinoma (ZR75, MCF7, MDA231), and neuroblastoma (IMR32)

This is the profile with the cleanest mechanism case

Pathogenesis of Age-Related Bone Loss in Humans

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10.1126/science.1123511 45 BonfiliL.CecariniV.GogoiO.BerardiS.ScarponaS.AngelettiM.et al