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The animals were treated immediately after injury and once daily until the 10 th day following injury with NaBPC157 (10 g, 10 ng/kg b.w., i.p.) or saline

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Others require the full escalation to maximum dose before seeing significant results

17 The presumed CYP3A-mediated kratom-quetiapine interaction has been reported previously and was so severe that quetiapine reached fatally supratherapeutic concentrations (12 mg/L)

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