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2.3 Other non-canonical bridging regulatory factors Other non-canonical autophagy regulatory proteins like Sestrin2 ( 2.3.1 Sestrin2 Sestrin2, a highly conserved protein belonging to the Sestrin family, is involved in multiple biological functions, including regulating redox reactions, metabolic homeostasis, and the aging process (Lee et al., 2013
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During osteoclast differentiation, the demand for iron increases, and the expression of TFR1 is increased through posttranscriptional regulation, thereby increasing iron uptake by the cell
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