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Weighted needle pinprick sensory thresholds: a simple test of sensory function in diabetic peripheral neuropathy

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In the Boyden chamber assay, TB4 stimulated keratinocyte migration 23-fold over medium alone after just 45 hours, with as little as 10 pg of TB4 sufficient to produce a potent stimulatory response

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This experimental drug is a small-molecule antagonist of the T-cell factor Tcf/-catenin complex that disrupt the critical proteinprotein interaction between -catenin and Tcf and also may decrease TGF-1 induced fibrotic markers expression in endometrial and endometriotic stromal cells [62]