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Description
Their role is best characterized in pancreatic beta cells where open K ATP channels maintain the membrane potential at a negative, hyperpolarized level [29]

PMID 35846210

Sakuranetin Prevents Acetaminophen-Induced Liver Injury via Nrf2-Induced Inhibition of Hepatocyte Ferroptosis

2017;12:e0177572

Extracellular cystine is the predominant precursor for intracellular cysteine, the availability of which limits GSH synthesis 21
The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress