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BMC Genomics 11 (1), 643

In particular, Cao and colleagues conducted a prospective cohort study (NCT00835341) to evaluate the predictive value of p16 methylation in patients diagnosed with oral epithelial dysplasia, demonstrating that the progression rates to OC were significantly higher in patients with p16 promoter hypermethylation compared to those with unmethylated p16 [278]

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In addition to be part of proteins, an important source of cysteine consumption is the synthesis of methionine and glutathione