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In our experiments both in vitro and in vivo, increased expression of GTRAP3-18 resulted in decreased GSH levels due to increased interaction with EAAC1 [59]

[DOI] [PubMed] [Google Scholar] [72].Petersen RC, Thomas RG, Grundman M, Bennett D, Doody R, Ferris S, Galasko D, Jin S, Kaye J, Levey A, Pfeiffer E, Sano M, van Dyck CH, Thal LJ

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This is largely accomplished by modifying the oxidation state of critical protein cysteine residues [5,18]

Reduced glutathione levels have been linked to conditions and problems including: Alzheimers Cancer Chronic liver disease Cognitive impairment Diabetes High blood pressure Infertility Mental health disorders Multiple sclerosis Parkinsons disease Neurodegenerative disorders Glutathione Basics Glutathione is a powerful antioxidant found in every cell in your body

EGCG also interacts with key proteins involved in apoptosis