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Mitochondrial disturbances, excitotoxicity, neuroinflammation and kynurenines: novel therapeutic strategies for neurodegenerative disorders

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4.3 Effect on neuro-developmental Throughout the developmental process, the brain exhibits heightened energy demands for synthesizing fundamental cellular structures, neurotransmitters, nucleic acids, proteins, carbohydrates, and lipids that are indispensable for neuronal growth and myelination (46, 47)