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Biol Trace Elem Res 204 , 22712284 (2026)

Under normal conditions, ROS and RNS serve as signaling molecules and are effectively neutralized by endogenous enzymatic antioxidants such as superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase, as well as nonenzymatic antioxidants like glutathione and vitamins C and E [118]

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Cytosolic concentrations were determined according to the following equation: Where V cell is the mean cell volume, m protein is the mean protein mass per dish measured in satellite dishes in each experiment, and c is the correlate of protein mass and cell number (7036 488 cells/g for A549 cells and 7092 830 cells/g for U87-MG cells)