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Liposomal formulations show modest improvements but still fall far below IV-achievable levels

[DOI] [PMC free article] [PubMed] [Google Scholar] 103.Persky V, Piorkowski J, Hernandez E, Chavez N, Wagner-Cassanova C, et al

Antisense oligonucleotides (ASOs) are single-stranded DNA or RNA molecules that regulate the activity of mRNA by binding to them

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Among these, GLUT1 is the most highly expressed in microglia and plays a key role in glucose uptake, especially under inflammatory conditions (Baik et al., 2019)

The protein is known to be involved in the maintenance of the redox balance, and may thus play an important role in the pathogenesis of psoriasis by regulating ROS [13]