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In hippocampal neurons exposed to the oxygenglucose deprivation and reoxygenation (OGD/R) model, propofol (0.150 M) restricted excessive mitochondrial fission by inhibiting dynamin-related protein 1 (Drp1) and fission protein 1 (Fis1) binding

This process of desensitization may continue to older age, according to the results of Acevedo et al

4.2.2 Ferroptosis exacerbates secondary brain injury post-ICH Secondary brain injury after ICH results from complex interplay between brain edema, neuroinflammation, oxidative stress, and programmed cell death including autophagy, apoptosis, and ferroptosis (193)

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It's a cheap, effective, and safe supplement [1] that deserves a place in many individuals' daily stacks for those reasons alone but today we're going to talk about one of its less-advertised benefits, thanks to a comprehensive literature review published recently in Nutrients , [2] citing nearly 100 studies