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To further investigate the systemic effect of low CoA on mitochondrial activity, we restricted Cse / mice to either 10% glucose or 10% galactose solution as their sole energy source in the drinking water after 6 days on control, no-Cys or no-Trp diets (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 225.Hausmann M., Obermeier F., Paper D., Balan K., Dunger N., Menzel K., Falk W., Schoelmerich J., Herfarth H., Rogler G

NU9056, a KAT 5 inhibitor, treatment alleviates brain dysfunction by inhibiting NLRP3 inflammasome activation, affecting gut microbiota, and derived metabolites in LPS-treated mice

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The supernatant was filtered through a 0.22 m filter to remove residual particles, with a portion of the filtrate transferred to a detection vial, where 20 L was used to prepare quality control (QC) samples, and the remainder was utilized for liquid chromatography-mass spectrometry (LC-MS) analysis