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Human Studies (See Table 5) A randomized, double-blind, placebo-controlled trial in 50 infertile male adults, with half given yellow maca extract (a total of 2.8 g/day) or placebo (consisting of milled apple fiber and sucrose in a 3:2 ratio), for 16 weeks reported that sperm concentration was improved by 40% (compared with placebo at 76%), although the results were not statistically significant [193]

ISCs are involved in electron transport, substrate binding, enzymatic catalysis and play critical roles in maintaining genomic stability since several DNA polymerases and helicases require interaction with ISCs for proper functioning

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10.1039/C6NR09810J 10.1039/C6NR09810J [DOI] [PubMed] [Google Scholar] Kowalska J, Rok J, Rzepka Z, Wrzeniok D (2021) Drug-induced photosensitivity-from light and chemistry to biological reactions and clinical symptoms