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For animal studies, mice were randomly assigned to experimental groups

doi: 10.1016/j.tem.2024.05.010 45 IslamAShaukatZHussainRGregorySL

We also summarize important polymorphisms of the pharmacogenes associated with APAP metabolism

In addition to GLS inhibitors, strategies targeting the conversion of glutamate into -ketoglutarate, such as GDH inhibitors and aminotransferase inhibitors, have also been evaluated in preclinical models of breast cancer and neuroblastoma [103-105]

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