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The deficiency of Nrf2 in Nrf2 knockout (KO) mice attenuated the chondroprotective effect of metformin on OA development, further affirming the core position of Nrf2 signaling during metformin fights illness as an antioxidant

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By a series of in vitro and in vivo studies, we demonstrated that STAG2 knockdown virtually had no effect on malignant phenotypes of BRAF-mutant thyroid cancer cells such as cell proliferation, colony formation and tumorigenic ability in nude mice compared with the control

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Vitamin C contributes to the normal function of the immune system