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According to the Global Burden of Disease Study 2023 [consistent with (2) but more precise], MDD affects approximately 280 million people globally, accounting for 3.6% of the total population

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Studies on interaction potency model based on drug synergy and therapeutic potential of triple stimuli-responsive delivery of doxorubicin and 5-fluoro-2-deoxyuridine against lymphoma using disulfide-bridged cysteine over mesoporous silica nanoparticles
