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Not only the activation and proliferation of T lymphocytes are related to ferroptosis, but the anti-tumor ability of T lymphocytes is also closely related to ferroptosis

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doi: 10.1016/s0896-6273(02)00733-x

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The expression of IL8 gene was upregulated in PQ-challenged cells, but its expression was substantially modulated with pretreatment of L-NAC and to a lesser extent with NAC (Table 2)

3.3 Innate immune pathways involved in melanoma (B16-F10) treatment with BCG In order to determine the role of innate immune pathways related to BCG immunotherapy in vivo , we compared our model in WT ( Figure 1A ) with different KO mice (TLR2 -/- , TLR3 -/- , TLR4 -/- , TLR7 -/- , TLR3/7/9 -/- , Caspase-1/11 -/- , Caspase-11 -/- , IL-1R -/- , cGAS -/- , STING -/- and IFNAR -/- )