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The GLP-1 class now includes multiple options at Defiance Health: Semaglutide (generic compounded, Wegovy, Ozempic) the original weight loss GLP-1, delivering 15-17% body weight loss on average at maintenance doses Tirzepatide (generic compounded, Zepbound, Mounjaro) a dual GIP/GLP-1 agonist, typically delivering 20-22% body weight loss at the highest dose Foundayo (orforglipron) FDA-approved April 1, 2026 , the first non-peptide GLP-1 pill that can be taken any time of day, with or without food