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Folic acid and vitamin B12 prevent deleterious effects of rotenone on object novelty recognition memory and kynu expression in an animal model of Parkinsons disease

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By upregulating key genes such as interleukin-17 (IL-17) and retinoic acid receptor-related orphan receptor gamma t (RORt), which are essential for Th17 cell differentiation and inflammation regulation, STAT3 effectively amplifies the inflammatory cascade reaction (Atreya et al., 2000

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Kotta-loizou I, Pritsa A, Antasouras G, Vasilopoulos SN, Voulgaridou G, Papadopoulou SK, et al

Whone AL, Watts RL, Stoessl AJ, Davis M, Reske S, Nahmias C, Lang AE, Rascol O, Ribeiro MJ, Remy P, Poewe WH, Hauser RA, Brooks DJ, REAL-PET Study Group (2003) Slower progression of Parkinsons disease with ropinirole versus levodopa: The REAL-PET study