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Acetyl-L-Carnitine Protects Blood-Brain Barrier From Alcohol Damage

However, the results of these two experiments are not particularly clear, indicating that LC supplementation has no significant effect on the improvement of liver function and quality of life in patients with HE, but it can appropriately improve the cognitive ability and some neurological function indicators of patients with HE [57,58]

Clinical trials and case studies demonstrate that triheptanoin improves symptoms for many patients with LC-FAOD (9, 10)

Carnitine analogs produced by the gut microbiota can colocalize with carnitine in the white matter of the brain and inhibit carnitine-mediated FAO in cell culture models of mouse CNS white matter, affecting the hosts nervous system, which provides a new perspective for understanding the complexity of the gutbrain axis [252]

Attenuation by acetyl-L-carnitine of neurological damage and biochemical derangement following brain ischemia and reperfusion. International journal of tissue reactions 21.1 (1999): 1-6