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Some more aggressive protocols (often in athletes or for acute injuries) may go up to 500 mcg daily or slightly higher during early weeks

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Erythrocyte and total leukocyte counts were measured using a haemocytometer

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Acknowledgements We are grateful to Tibor Pli and Andrs Dr from the Institute of Biophysics, HUN-REN Biological Research Centre for providing access to the spectrofluorometer Fluorolog 3 (Horiba Jobin Yvon) and to the Malvern Zetasizer Nano ZS device (Malvern Instruments)

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