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Investigations to elucidate the missing links between the PK, surrogates of response, and ultimate clinical response have the potential to increase the direct impact of the literature reviewed in this report

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In addition, hepatoma cells with low expression of glutamic oxalacetic transaminase 2 (GOT2) showed sensitivity to the glutaminase inhibitor CB-839

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2016 doi: 10.1016/j.bbadis.2016.01.003
