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TUDCA was also proved to attenuate PKM2 pathway activation in proinflammatory microglia and inhibited the expression of IL-6, IFN- and high mobility group protein 1 (HMGB1) in lesion center [138]

Turner and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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Iohara KM, Zayed Y, Takei H, Watanabe M, Nakashima

[DOI] [PMC free article] [PubMed] [Google Scholar] 127.Ruchko MV, Gorodnya OM, Zuleta A, Pastukh VM, Gillespie MN

Notably, the 5-LOX inhibitor zileuton has been shown to mitigate retinal damage and RPEC degeneration caused by NaIO 3 by suppressing ferroptotic mechanisms (175)