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Pre-existing gastrointestinal conditions People with irritable bowel syndrome, gastroparesis, gastroesophageal reflux disease, or chronic constipation are significantly more likely to experience early and intense side effects

The increase of ROS within a high oxidative stress level (by decreasing of the antioxidant GPx enzyme) increases the possibility of lipid oxidation, especially LDL-cholesterol and thus favors the formation of anti-LDL-oxidized cholesterol antibodies, which will lead to the initiation of an immune and vascular aggression process (13-18)

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Key Takeaway: Long-term glutathione use is widely considered safe

These results may be explained by an animal study conducted by Attri et al

If you suspect you are experiencing glutathione toxicity symptoms, it is crucial to consult with a healthcare professional for a proper diagnosis