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Enhancement of purine nucleotide synthesis via the pentose phosphate pathway was found to be advantageous for cell proliferation and tumorigenesis of NRF2-addicted cancer cells (Mitsuishi et al

Mitochondria play essential roles in intracellular protection against oxidative stress-which molecules among the ROS generated in the mitochondria can escape the mitochondria and contribute to signal activation in cytosol

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10.1016/S0092-8674(00)00143-4 72 MaJ.PanP.AnyikaM.BlaggB

Adequate glutathione levels are important for a strong and properly functioning immune response