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In addition, APP/PS1 animals lacking C1q showed decreased levels of glial activation and a reduction in hippocampal neuron loss (Fonseca et al., 2004)

Edwards S, Little HJ, Richardson HN, Vendruscolo LF

Supplementary materials and methods, figures

Longitudinal studies would also be beneficial, as theyre critical to evaluate longterm effects of senolytic treatment on the overall health status of the patient

In areas with combined selenium and iodine deficiencies, selenium deficiency may reduce fetal hypothyroidism by reducing maternal T4 metabolism, offering protection to fetal brain development