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for example, our body temperature

Asian Pac J Cancer Prev 15(1):495499

Genesis of both neurodegenerative diseases has not been elucidated and several endogenous (genetic) and exogenous (environment) factors contribute to the onset and/or development of these illnesses, which highlights the necessity to expand the research on identifying the environmental risk factors that predispose to the development of these neurodegenerative diseases

Together with the reduction of antioxidant defenses, these mechanisms highlight the role of oxidative stress as an important player in the development and progression of depression [4]

The human MAPEG superfamily includes six members: 5lipoxygenase activating protein (FLAP), leukotriene C 4 synthase (both involved in leukotriene synthesis), MGST1, MGST2, MGST3 (GSTs as well as glutathione dependent peroxidases) and prostaglandin E synthase (PGES) (Bresell et al., 2005)

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