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The result is a conjugated metabolite that is more water soluble than the original xenobiotic or Phase I metabolite

Nitric oxide synthesis is increased in patients with systemic lupus erythematosus

While designed to manage sweat and odour, repeated use can gradually disrupt the skin barrier, particularly if the skin is already sensitised by shaving or friction

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Apoptosis of granulosa cells is higher in patients, which may be associated to decreased serum testosterone levels