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An increase in the activity of pro-oxidant enzymes ( nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX), xanthine oxidase (XO)), impaired glutathione metabolism ( total glutathione, oxidized glutathione (GSSG), reduced glutathione (GSH), redox status), higher levels of oxidative stress ( total thiols, malondialdehyde (MDA), lipid hydroperoxides (LOOHs)), total antioxidant status (TAS)), carbonyl stress ( dityrosine, N-formylkynurenine) and nitrosative stress ( nitric oxide (NO), S-nitrosothiols, peroxynitrite, nitrotyrosine), as well as an intensified systemic inflammatory response ( interleukin (IL)-1, IL-6), were observed in maxillofacial surgery patients

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Bioche 52, 169178

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C., & Stefanski, A

Adesanya AW, Beauchamp MJ, Lavine MD, Lavine LC, Zhu F, Walsh DB