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295 , R781R788 (2008)

KLOW binds to klotho receptors expressed in kidney, liver, adipose tissue, and vascular endothelium
Small-molecule XIAP inhibitors derepress downstream effector caspases and induce apoptosis of leukemia cell lines and patient samples
Cyclosporin A improves brain tissue oxygen consumption and learning/memory performance after lateral fluid percussion injury in rats

doi: 10.1038/s41698-025-00896-8 39 ZhengXLiuXZhangXZhaoZWuWYuS
The signaling logic is conserved
