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This guarantees the shot is deposited directly into the muscle.

This process leads to a rapid loss of synaptic NMDARs without overt neuronal death, resulting in severe but often reversible neuropsychiatric symptoms, including memory impairment, seizures, and psychosis

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This is observed as well in our series of patients, as Supplementary Table 1 demonstrates, although we have not been able to objectively show muscle weakness in our cohort