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Projections for prevalence of Parkinson's disease and its driving factors in 195 countries and territories to 2050: modelling study of Global Burden of Disease Study 2021

The GST regulation is helpful in treating psoriasis, with anti-inflammatory effect on the keratinocytes hyperproliferation and in modulation of metabolic comorbidity

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190 Hyperuricemia and diseases An elevated uric acid concentration above physiological levels can pose a potential risk factor for several diseases closely associated with metabolic disorders

Notably, reverse experiments confirmed that downregulating SLC7A11 significantly increased baseline ROS levels and induced ferroptosis, offering a theoretical basis for targeting the SLC7A11 - GSH axis to reverse TMZ resistance
