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In the MPTP mouse model, NRF2 activation has been associated with a reduction in oxidative stress (Williamson et al., 2012), induction of antioxidant enzymes (Jazwa et al., 2011), and improvement of the mitochondrial respiratory rate (Fu et al., 2018)
The challenge is that both options serve different goals

Hamlin, J.C., et al

The higher levels of ROS can also be caused by oncogenes such as constitutively active isoforms of RAS , and oncogenic K-RAS have been found to be necessary for precancerous lesions in the pancreas and for lung adenocarcinoma formation [35,36]

BPC-157 (Body Protection Compound-157) Research Focus: Investigated for its influence on tissue matrix dynamics, angiogenesis modulation, and gastrointestinal tract cellular stability