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204,206 Statins Statins are a family of cholesterol-lowering drugs that includes atorvastatin (Lipitor), lovastatin (Mevacor), simvastatin (Zocor), and others

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However, several recent studies demonstrate that hyperactivation of the Nrf2 signaling cascade favors the survival of both normal and malignant cells, protecting them against oxidative stress, and chemotherapeutic agents [40, 41]

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Nat Protoc 2013

Li O, Renault S, Aug-Gouillou C
