a melanotic macule at the wet–dry line of the lower lip. b Melanotic Oral melanotic macule - Stock
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Walling HW, Scupham RK, Bean AK, Ceilley RI

Lower gastrointestinal side effects such as constipation and diarrhea are less dose-related and are managed by symptom specific remedies (e.g

doi: 10.1111/andr.12652 [DOI] [PubMed] [Google Scholar] 107

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Dietary modifications and supportive therapies may also be necessary to manage symptoms and prevent complications

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