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This finding opens new avenues for understanding neurological diseases such as anti-NMDAR encephalitis

Peak plasma concentration (Cmax) occurs approximately 6090 minutes post-injection, coinciding with maximal MC1R occupancy in target tissues

2019 Jul;67(1):11-15

We postulate that the ionization of the lipid caused lower retention of the RNA, which then resulted in lower transfection and in vivo delivery efficiencies, as confirmed by the failure to induce an antibody response against HIV-1 Env gp140

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Hudson & Tabet 2003 Cochrane Review: A Cochrane Review of 15 clinical trials (including 13 of those in the meta-analysis above) assessed 1 to 3 g/day ALCAR supplementation versus placebo over 12 to 52 weeks in participants with mild to moderate dementia or cognitive decline