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Involvement of endogenous prostaglandins and gastric secretion

This search tentatively identified two additional metabolites, including a glutamyl conjugate of the nucleoside acadesine that was identified in 643 samples, and brought the total number of metabolites discovered in these studies to 36 (Extended Data Fig

Yan B, Ai Y, Sun Q, Ma Y, Cao Y, Wang J, et al

Interestingly, other characteristics, such as race and tumor location, are negative prognostic factors that are well established in the literature, and that are not yet considered in current staging systems [11,15,131]

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