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In addition, while carnitine supplementation may be beneficial in some cases, excessive intake may bring potential side effects

Patients with chronic myelogenous leukemia (CML) and high expression of CD36 often have worse prognoses [89], higher levels of FAO in the leukemia stem cell subgroup of CML, and resistance to AraC, but the specific relationship between FAO and drug resistance and its mechanism is still unclear [90]

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2025 Sep 6:165:115445

By increasing the amount of L-carnitine present, more fatty acids can be shuttled to be used as a source of energy, which helps with weight management.Additionally, L-carnitine may be useful for increasing endurance in athletes

Table 22.1 summarizes clinical considerations for CMN