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10.1016/j.molcel.2020.11.024 102 YangJ.AntinP.BerxG.BlanpainC.BrabletzT.BronnerM.et al (2020)

This interaction does not involve hydrogen bond, but it involves hydrophobic interaction with the residues in HMGB1 binding site, including: Ala69, Glu72, Arg73, and Lys76 (Table 2, Fig

It is characterized by absolute or relative deficiencies in insulin secretion and/or insulin action and is associated with chronic hyperglycemia and disturbances of carbohydrate, lipid, and protein metabolism

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MS data was acquired using a data-dependent top20 method dynamically choosing the most abundant precursor ions from the survey scan (3001800 m/z) for HCD fragmentation