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Description
Pharmacotherapy 39 , 4054 (2019)

[DOI] [PubMed] [Google Scholar] 134.Mekki K., Taleb W., Bouzidi N., Kaddous A., Bouchenak M

It is a lipid repair enzyme that functions to detoxify lipid hydroperoxides, which are harmful reactive oxygen species (ROS) generated during oxidative stress
For their part, Alzheimers researchers are assessing intranasal preparations of galantamine, deferoxamine, tacrine, tarenflurbil, rivastigmine, risperidone, curcumin, quercetin, piperine, and insulin

NAD+ Restoration: By blocking NNMT, 5-Amino-1MQ prevents the degradation of Nicotinamide, allowing it to be recycled back into NAD+ via the salvage pathway

Phase 3 trials include a 4mg maintenance arm specifically because some individuals achieve excellent results at lower doses
