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Mercaptosuccinate is one of the most effective and widely used of the related mercaptans that inhibit GPx-1 by competing with GSH for binding to the active-site Sec (62)

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Acidic and hypoxic tumor microenvironment regulation by CaO(2)-loaded polydopamine nanoparticles

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Modulation of CYP51A1 The expression and activity of CYP51A1 are tightly regulated through both transcriptional mechanisms and post-translational modifications (PTMs), including ubiquitin-mediated degradation and proteinprotein interactions (PPI) (Fig