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doi: 10.1001/jamanetworkopen.2020.19722 42 MessikaJ.SztrymfB.BertrandF.Billard-PomaresT.BarnaudG.BrangerC.et al
Oncogenic phosphatidylinositol 3-kinase (PI3KCA) mutations activate protein kinase B (AKT), which phosphorylates xCT at serine 26 to suppress cystine/glutamate antiport [5]
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