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Epub 2012/08/07
To better understand the molecular nature of the interaction between MraY and its membrane-embedded substrates, we carried out extensive MD simulations of the MraY dimer (PDB ID: 5CKR) in a model lipid bilayer containing C 55 -P, lipid I or both (see Methods)
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Senescent human fibroblasts show increased glycolysis and redox homeostasis with extracellular metabolomes that overlap with those of irreparable DNA damage, aging, and disease

[DOI] [PMC free article] [PubMed] [Google Scholar] Haataja T.J.K., Koski M.K., Hiltunen J.K., Glumoff T