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FABP5 is abundantly expressed in keratinocytes, adipocytes, macrophages, T cells, and cancer cells 18,26,30,31

Consistent with our structural findings, the activation of AMPARs is much better coupled to the release of a quantum of glutamate than NMDARs 13

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Thus, treatment of AD using a multi-cannabinoid strategy (such as whole plant cannabis extracts or particular CBD:THC combinations) may be more efficacious compared to cannabinoid isolate treatment strategies

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