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Abdominal exam is notable for tenderness to palpation in the right upper quadrant with mild hepatomegaly

LCMS data confirmed an equivalent metabolic time trajectory towards radiation response at D9 (p = 6.39 10 4 ) as shown in Supplementary Fig

Example: Consider a cache with 3 blocks and a reference string: 4, 0, 3, 2, 1, 3, 0, 4 Load 4, 0, 3 Cache = [4, 0, 3] Next 2 Evict 4 (farthest in future) Cache = [2, 0, 3] Next 1 Evict 2 Cache = [1, 0, 3] Next 3 Hit Cache = [1, 0, 3] Next 0 Hit Cache = [1, 0, 3] Next 4 Evict 1 Cache = [4, 0, 3] Next 0 Hit Cache = [4, 0, 3] OPT gives the minimum possible cache misses but is impractical since future accesses are unknown

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10.1016/S0272-6386(03)00113-6 [DOI] [PubMed] [Google Scholar] 50.Tomassini V, Pozzilli C, Onesti E, Pasqualetti P, Marinelli F, Pisani A, et al