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[DOI] [PubMed] [Google Scholar] 278.Chou C.-Y., Kuo H.-L., Yung Y.-F., Liu Y.-L., Huang C.-C

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599 In a randomized placebo-controlled trial in 102 middle-aged participants with pre-hypertension, taking 106 mg of aronia polyphenols daily for 12 weeks resulted in improved endothelial function, as well as changes to the gut microbiome with a shift toward increased presence of beneficial bacteria

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In case of autoimmune components, auto-antibodies directed at fetal brain proteins might cause BBB damage (Zimmerman et al., 2007)