how to inject b12 shots in your abdomen Self-Inject Vitamin at Home Instruction Guide for Intramuscular (IM)

In most cases, yes

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FDA.gov

B12 Injections are safe and effective when administered by our trained professionals

For example , this includes older adults, vegans, and people with gut disorders that block nutrient absorption

For this reason, patients with Parkinsons disease on levodopa therapy should avoid high B intake unless they are also taking carbidopa (which prevents this interaction)