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Phase 1 corresponds to a high level of activity in the primary afferent as a result of C-fiber activation due to peripheral stimulation, whereas phase 2 results from a continuous low-level small afferent input, together with a facilitated state of spinal processing [21]

Liu Z, Guo J, Sun H, Huang Y, Zhao R, Yang X (2015) Biochimie -lipoic acid attenuates LPS-induced liver injury by improving mitochondrial function in association with GR mitochondrial DNA occupancy

Additionally, the great variability in the studied populations, with different nutritional statuses according to the income level of the country of birth, make it difficult to obtain clear results

The studies documented that fat mass reduction occurred without corresponding changes in lean tissue mass

Dose adjustments based on age are pure speculation