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Clonidine is a drug used to treat high blood pressure, ADHD, anxiety disorders, tic disorders, withdrawal (from either alcohol, opioids, or smoking), migraine, and certain pain conditions, with largely tolerable adverse effects (Fankhauser et al., 1992

Pancreatic insufficiency can make it hard for B12 to be released from food proteins

[DOI] [PubMed] [Google Scholar] 53.Wu D.-T., Xie J., Wang L.-Y., Ju Y.-J., Lv G.-P., Leong F., Zhao J., Li S.-P

E., Kreider, R

Folate, which is present in foods as a polyglutamate conjugate, undergoes hydrolysis in the intestinal mucosa to its monoglutamate form, which serves as the transport form of folate (Figure 1)

This allows the vitamin to be absorbed directly into the bloodstream without having to go through the digestive system, reducing the risk of malabsorption in the stomach